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Company ReportsJazz Pharmaceuticals

Jazz Pharmaceuticals(JAZZ)

Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is a biopharmaceutical company based in Ireland. It was founded in 2003. One of the company's considerable products is the United States Food and Drug Administration (FDA) approved drug Xyrem (sodium oxybate), the sodium salt of the naturally occurring neurotransmitter γ-Hydroxybutyric acid (GHB). In 2017, net product sales of Xyrem were $1.187 billion, which represented 74% of the company's total net product sales. In 2019, Jazz was granted FDA-approval to market Sunosi with indications for treating excessive daytime sleepiness (EDS) in narcolepsy as well as obstructive sleep apnea (OSA). In 2022, it was announced that Axsome Therapeutics would be acquiring Sunosi from Jazz Pharmaceuticals

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Defitelio	Defibrotide	2016-03-30	2032	Hepatic veno-occlusive disease
Erwinaze	Asparaginase erwinia chrysanthemi	2011-11-18		—
Fazaclo	Clozapine	2004-02-10	2028	Schizophrenia , Psychotic disorders , Bipolar disorder , Schizophrenia spectrum and other psychotic disorders
Luvox	Fluvoxamine	2008-02-28		Panic disorder, Obsessive-compulsive disorder, Depressive disorder
Rylaze	Asparaginase erwinia chrysanthemi (recombinant)	2021-06-30		Precursor cell lymphoblastic leukemia-lymphoma
Vyxeos (previously vyxeos)	Cytarabine, Daunorubicin	2018-08-23	2025-2032	Leukemia, Myeloid leukemia acute, Lymphoma, Precursor cell lymphoblastic leukemia-lymphoma, Meningeal neoplasms
Xyrem	Oxybate	2002-07-17	2024-2042	Narcolepsy, Cataplexy
Xywav	Magnesium oxybate, Oxybate, Potassium oxybate	2020-07-21	2024-2042	Narcolepsy, Cataplexy
Zepzelca	Lurbinectedin	2020-06-15	2029	Small cell lung carcinoma
Epidyolex	Cannabidiol	2019-09-19	2035-2041	Pain, Myoclonic epilepsies, Lennox gastaut syndrome, Anxiety
Enrylaze	Crisantaspase	2023-09-15		Precursor cell lymphoblastic leukemia-lymphoma
Epidiolex	Cannabidiol	2018-09-28	2035-2041	Pain, Myoclonic epilepsies, Lennox gastaut syndrome, Anxiety

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

small cell carcinoma

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

,

,

,

,

neuroendocrine carcinoma

,

gastrointestinal diseases

,

urologic neoplasms

,

transitional cell carcinoma

,

desmoplastic small round cell tumor

,

,

small cell lung carcinoma

healthy volunteers/patients

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

pharmacokinetics

,

,

lewy body disease

,

frontotemporal lobar degeneration

,

primary progressive nonfluent aphasia

,

pure autonomic failure

,

appetitive behavior

,

,

kidney diseases

,

,

driving under the influence

,

orthostatic hypotension

,

diabetic retinopathy

,

renal insufficiency

,

chronic renal insufficiency

,

,

status epilepticus

,

interstitial cystitis

,

,

alcohol withdrawal delirium

,

behavioral symptoms

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

gastrointestinal stromal tumors

,

,

,

,

retinal degeneration

,

squamous cell carcinoma of head and neck

,

,

hepatic insufficiency

,

non-hodgkin lymphoma

,

waldenstrom macroglobulinemia

,

,

,

disease progression

,

respiratory aspiration

,

,

,

alopecia areata

,

,

,

chronic kidney failure

,

anorexia nervosa

,

drinking behavior

,

retinal diseases

,

therapeutic equivalency

,

,

,

tobacco use cessation

,

,

headache disorders

,

,

,

hypercholesterolemia

,

metabolic syndrome

,

,

,

reflex epilepsy

,

mouth neoplasms

,

biological availability

,

skin absorption

,

metabolic bone diseases

,

musculoskeletal diseases

,

endometrial neoplasms

,

testicular neoplasms

,

chemical and drug induced liver injury

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

somatoform disorders

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

type 1 diabetes mellitus

,

,

opioid-related disorders

,

corticobasal degeneration

,

,

shy-drager syndrome

,

multiple system atrophy

,

,

,

parkinsonian disorders

,

,

wounds and injuries

,

traumatic brain injuries

,

,

macular degeneration

,

,

,

,

,

,

pervasive child development disorders

,

psychomotor agitation

,

,

ulcerative colitis

,

,

graft vs host disease

,

attention deficit disorder with hyperactivity

,

diabetes mellitus

,

,

,

multiple myeloma

,

prostatic neoplasms

,

,

,

,

,

,

,

,

rheumatoid arthritis

,

,

liver neoplasms

,

plasma cell neoplasms

,

colonic neoplasms

,

post-acute covid-19 syndrome

,

schizophrenia spectrum and other psychotic disorders

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

ovarian neoplasms

,

,

,

sickle cell anemia

,

communicable diseases

,

addictive behavior

,

essential tremor

,

,

psoriatic arthritis

,

retinitis pigmentosa

,

,

,

,

huntington disease

,

,

central nervous system diseases

,

movement disorders

,

consciousness disorders

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

chronic periodontitis

,

,

tobacco use disorder

,

tobacco smoking

,

,

,

rectal neoplasms

,

gallbladder neoplasms

,

intellectual disability

,

child behavior disorders

,

,

,

,

,

recovery of function

,

heroin dependence

,

chronic urticaria

,

,

neurocognitive disorders

,

,

colorectal neoplasms

,

uterine neoplasms

,

ovarian epithelial carcinoma

,

substance withdrawal syndrome

,

autoimmune hepatitis

,

,

,

dual (psychiatry) diagnosis

,

coronavirus infections

,

severe acute respiratory syndrome

,

,

,

,

chronic traumatic encephalopathy

,

,

,

hidradenitis suppurativa

,

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

exercise tolerance

,

marijuana smoking

,

,

type 2 diabetes mellitus

,

pheochromocytoma

,

geographic atrophy

,

oculocutaneous albinism

,

,

congenital pain insensitivity

,

hereditary sensory and autonomic neuropathies

,

,

neurotoxicity syndromes

,

,

,

female infertility

,

,

,

dystonic disorders

,

,

,

trichotillomania

,

hoarding disorder

,

,

,

brain neoplasms

,

,

,

,

digeorge syndrome

,

22q11 deletion syndrome

,

hiv seropositivity

,

,

affective symptoms

,

medical sociology

,

carpal tunnel syndrome

,

neuromyelitis optica

,

carcinoma in situ

,

breast carcinoma in situ

,

ductal carcinoma breast

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

rotator cuff injuries

,

post-traumatic epilepsy

,

hepatocellular carcinoma

,

marijuana abuse

,

,

,

progressive supranuclear palsy

,

,

post-traumatic stress disorders

,

substance-related disorders

,

,

choledocholithiasis

,

alzheimer disease

,

,

traumatic stress disorders

,

psychotic disorders

,

peripheral nervous system diseases

,

autism spectrum disorder

,

breast neoplasms

,

autistic disorder

,

drug resistant epilepsy

,

sleep wake disorders

,

,

,

mental disorders

,

spinal cord injuries

,

sleep initiation and maintenance disorders

,

,

bipolar disorder

,

tourette syndrome

,

,

endoscopic retrograde cholangiopancreatography

,

,

diabetic neuropathies

,

,

musculoskeletal pain

,

,

,

fragile x syndrome

,

palliative care

,

nervous system diseases

,

problem behavior

,

temporomandibular joint disorders

,

,

,

,

infantile spasms

,

inflammatory bowel diseases

,

prader-willi syndrome

,

neurodegenerative diseases

,

,

pathologic constriction

,

,

,

temporomandibular joint dysfunction syndrome

,

,

,

,

atopic dermatitis

,

,

,

replacement arthroplasty knee

,

autonomic nervous system diseases

,

primary dysautonomias

,

,

angelman syndrome

,

bile duct diseases

,

,

heart disease risk factors

,

,

cardiovascular diseases

,

epidermolysis bullosa

,

wasting syndrome

,

,

,

,

psychological burnout

,

,

bipolar and related disorders

,

,

postoperative nausea and vomiting

,

overactive urinary bladder

,

familial dysautonomia

,

,

vascular dementia

,

,

tension-type headache

,

neoplasm metastasis

,

electromyography

,

occlusal splints

,

severe acute respiratory syndrome-related coronavirus

,

,

,

urinary calculi

,

,

,

,

,

,

stroke rehabilitation

,

postural orthostatic tachycardia syndrome

,

,

orthostatic intolerance

,

stress fractures

,

,

male breast neoplasms

,

,

,

systemic scleroderma

,

diffuse scleroderma

,

mucopolysaccharidoses

,

mucopolysaccharidosis iii

,

parkinson disease

,

,

,

,

,

multiple sclerosis

,

anxiety disorders

,

,

,

,

,

muscle spasticity

,

,

knee osteoarthritis

,

myoclonic epilepsies

,

,

lennox gastaut syndrome

,

,

cognitive dysfunction

,

alcohol drinking

,

depressive disorder

,

,

postoperative pain

,

,

cocaine-related disorders

,

,

,

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

pancreatic neoplasms

,

myofascial pain syndromes

,

tuberous sclerosis

,

migraine disorders

,

,

,

,

major depressive disorder

,

drug interactions

,

neuroinflammatory diseases

,

absence epilepsy

,

neurologic gait disorders

,

,

bile duct neoplasms

,

,

treatment-resistant depressive disorder

,

motor disorders

,

ankle fractures

,

tibial fractures

,

,

dysthymic disorder

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

impulse control disruptive and conduct disorders

,

,

ischemic optic neuropathy

,

optic nerve diseases

,

secondary headache disorders

,

treatment adherence and compliance

,

,

,

cholecystolithiasis

,

acalculous cholecystitis

,

acute cholecystitis

,

cholangiocarcinoma

,

pathologic dilatation

,

nociceptive pain

,

biliary tract diseases

,

,

obstructive jaundice

,

,

,

endoscopic sphincterotomy

,

,

,

common bile duct neoplasms

,

personality disorders

,

cholecystectomy

,

,

,

,

alcoholic intoxication

,

,

,

irritable bowel syndrome

,

x-linked genetic diseases

,

,

,

memory consolidation

,

,

adolescent development

,

alcohol-related disorders

,

alcohol abstinence

,

postcholecystectomy syndrome

,

,

biliary fistula

,

intrahepatic cholestasis

,

ampulla of vater cancer

,

,

,

consumer behavior

,

head and neck neoplasms

,

intractable pain

,

,

hippocampal sclerosis

,

,

,

,

blood coagulation disorders

,

von willebrand diseases

,

hemostatic disorders

,

,

,

genetic predisposition to disease

,

,

,

,

late onset disorders

,

hematologic neoplasms

,

,

common bile duct diseases

,

,

atherosclerosis

,

alcohol drinking in college

,

underage drinking

,

glucose metabolism disorders

,

metabolic diseases

,

lipid metabolism disorders

,

compassion fatigue

,

,

,

pregnancy complications

,

,

electroencephalography

,

,

,

,

maternal mortality

,

,

,

,

,

laparoscopic cholecystectomy

,

,

,

immune system diseases

,

,

ultrasonography

,

,

pneumoperitoneum

,

respiratory distress syndrome

,

severe acute respiratory syndrome-related coronavirus

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

,

neurotoxicity syndromes

,

graft vs host disease

,

,

vascular diseases

,

thrombotic microangiopathies

,

hepatic veno-occlusive disease

t-cell lymphoma cutaneous

,

hypersensitivity

,

leukemia myeloid chronic atypical bcr-abl negative

,

neutrophilic leukemia chronic

,

colorectal neoplasms

,

rectal neoplasms

,

neoplasms by histologic type

,

,

,

biphenotypic leukemia acute

,

,

myeloid leukemia accelerated phase

,

primary myelofibrosis

,

aids-related lymphoma

,

nervous system neoplasms

,

b-cell lymphoma marginal zone

,

pathologic complete response

,

prolymphocytic leukemia t-cell

,

prolymphocytic leukemia

,

,

,

adult t-cell leukemia-lymphoma

,

peripheral blood stem cell transplantation

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

brain neoplasms

,

,

pseudoxanthoma elasticum

,

,

hematologic diseases

,

,

plasma cell leukemia

,

aplastic anemia

,

immunoblastic lymphadenopathy

,

lymphoproliferative disorders

,

congenital abnormalities

,

,

enteropathy-associated t-cell lymphoma

,

neurotoxicity syndromes

,

second primary neoplasms

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

hepatocellular carcinoma

,

healthy volunteers/patients

,

vascular calcification

,

,

familial hypophosphatemic rickets

,

hypophosphatemic rickets

,

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

medulloblastoma

,

,

clonal hematopoiesis

,

,

,

prolymphocytic leukemia b-cell

,

,

autoimmune diseases

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

autologous transplantation

,

neuromyelitis optica

,

myasthenia gravis

,

ocular motility disorders

,

polyneuropathies

,

muscle weakness

,

,

stiff-person syndrome

,

central nervous system vasculitis

,

spinocerebellar degenerations

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

lambert-eaton myasthenic syndrome

,

opsoclonus-myoclonus syndrome

,

,

prostatic neoplasms

,

,

hiv seropositivity

,

behavior therapy

,

intestinal neoplasms

,

radiation effects

,

phenylketonurias

,

,

,

,

,

hemophagocytic lymphohistiocytosis

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

liver neoplasms

,

systemic lupus erythematosus

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

respiratory aspiration

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

intestinal diseases

,

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia acute

,

hematologic neoplasms

,

myeloproliferative disorders

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

megakaryoblastic leukemia acute

,

,

multiple myeloma

,

t-cell lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

neoplasm metastasis

,

plasma cell neoplasms

,

myelodysplastic-myeloproliferative diseases

,

follicular lymphoma

,

t-cell lymphoma peripheral

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia chronic-phase

,

refractory anemia with excess of blasts

,

residual neoplasm

,

central nervous system neoplasms

,

basophilic leukemia acute

,

,

hypereosinophilic syndrome

,

,

eyelid neoplasms

,

t-cell leukemia

,

eosinophilic leukemia acute

,

refractory anemia

,

myeloid sarcoma

,

,

thrombocytopenia

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

,

langerhans-cell histiocytosis

,

multiple sclerosis

,

,

b-cell leukemia

,

drug-related side effects and adverse reactions

,

,

induction chemotherapy

,

classical conditioning

,

relapsing-remitting multiple sclerosis

,

gata2 deficiency

,

,

breast neoplasms

,

,

hematopoietic stem cell mobilization

,

,

bone marrow transplantation

,

chronic progressive multiple sclerosis

,

non-small-cell lung carcinoma

,

,

,

leukemoid reaction

,

whole-body irradiation

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myelodysplastic syndromes

,

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

mantle-cell lymphoma

,

hodgkin disease

,

myelomonocytic leukemia chronic

,

burkitt lymphoma

,

myelomonocytic leukemia juvenile

,

philadelphia chromosome

,

promyelocytic leukemia acute

,

hematopoietic stem cell transplantation

,

large-cell lymphoma anaplastic

,

,

meningeal carcinomatosis

,

,

graft vs host disease

,

,

waldenstrom macroglobulinemia

,

meningeal neoplasms

,

,

,

cardiovascular diseases

,

,

,

acute coronary syndrome

,

vascular diseases

,

cerebral infarction

,

atherosclerosis

,

,

mediastinal neoplasms

,

acquired immunodeficiency syndrome

,

communicable diseases

,

,

,

sickle cell anemia

,

hemoglobin sc disease

,

hemoglobin c disease

,

paroxysmal hemoglobinuria

,

,

,

extranodal nk-t-cell lymphoma

,

sezary syndrome

,

mycosis fungoides

,

hairy cell leukemia

,

intraocular lymphoma

,

large granular lymphocytic leukemia

,

lymphomatoid granulomatosis

,

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

parkinson disease

,

parkinsonian disorders

,

hip osteoarthritis

,

knee osteoarthritis

,

,

electric stimulation therapy

,

precancerous conditions

,

,

chromosome aberrations

,

chromosome disorders

,

,

,

prediabetic state

,

diabetes mellitus

,

hypercholesterolemia

,

hyperhomocysteinemia

,

cognitive dysfunction

,

language development disorders

,

,

auditory perceptual disorders

,

,

beta-thalassemia

,

chronic kidney failure

,

renal insufficiency

,

erectile dysfunction

,

,

,

eye abnormalities

,

gastrointestinal microbiome

,

spontaneous abortion

,

Asparaginase erwinia chrysanthemi

philadelphia chromosome

,

,

non-hodgkin lymphoma

,

hematologic neoplasms

,

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

hypersensitivity

philadelphia chromosome

,

,

non-hodgkin lymphoma

,

hematologic neoplasms

,

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

hypersensitivity

urologic neoplasms

,

,

transitional cell carcinoma

drug interactions

healthy volunteers/patients

,

,

actinic keratosis

,

large b-cell lymphoma diffuse

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

,

,

,

hodgkin disease

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

renal cell carcinoma

,

,

,

,

chronic hepatitis b

,

communicable diseases

,

,

parkinson disease

,

parkinsonian disorders

,

movement disorders

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

chronic renal insufficiency

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

graft vs host disease

,

type 1 diabetes mellitus

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

brain neoplasms

,

,

oligodendroglioma

,

pancreatic neoplasms

,

,

neuroendocrine tumors

,

islet cell carcinoma

,

,

,

somatostatinoma

,

,

,

breast neoplasms

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

,

retinal vein occlusion

,

vision disorders

,

,

macular degeneration

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

juvenile arthritis

,

,

kidney diseases

,

myocardial infarction

,

,

inferior wall myocardial infarction

,

organ transplantation

,

wet macular degeneration

,

neoplasm metastasis

,

graft rejection

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

non-alcoholic fatty liver disease

,

,

postoperative pain

,

,

choroidal neovascularization

,

pathologic neovascularization

,

chronic kidney failure

,

renal insufficiency

,

liver transplantation

,

kidney transplantation

,

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

liver cirrhosis

,

,

atrial fibrillation

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